Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Fellermann K, Ganz T, Stange EF, Bevins CL: Reduced Paneth cell -defensins in ileal Crohn's disease
The peptide comes in lyophilized (freeze-dried) powder form and needs to be reconstituted with bacteriostatic water before use
Orforglipron Orforglipron is a once-daily, oral, non-peptide GLP-1 RA (small molecule) which interacts with the GLP-1 receptor in a slightly different manner compared to native GLP-1
It reduces inflammation, stimulates cell growth, and increases blood flow to the injured area, creating an optimal environment for tissue repair
Activation of this pathway increases the cells ability to neutralize ROS before they can damage proteins, lipids, or DNA
Talking to your doctor about your supplements is a must if youre on immunotherapy